Praxis Precision Medicines

IT Support Specialist, Tier II - US based

United States - Remote

Role brief

What this role is asking for.

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed. The Opportunity The Tier II IT Support Specialist is a key player in delivering seamless technology experiences across Praxis. Youโ€™ll serve as the primary escalation point for complex technical issues, partnering closely with our internal IT support, development, and leadership teams to ensure smooth operations for our 260โ€“400 users. From managing identity and access to administering collaboration platforms and overseeing IT assets, this role is essential to sustaining and scaling our tech infrastructure. This is a hands-on, high-impact position for someone who thrives on solving problems, documenting what works, and improving how we support our mission. Primary Responsibilities Serve as the go-to escalation point for Level 2 IT issues from our internal Helpdesk Troubleshoot and resolve complex problems across Microsoft 365, collaboration tools, and endpoint devices Support onboarding and offboarding workflows for employees, consultants, and contractors Administer user access and authentication across Microsoft Entra ID and SaaS platforms Manage SSO, MFA, password managers (1Password), certificates, and guest access Handle admin consent requests and configure access for contractors and temporary roles Administer permissions for SharePoint, DocuSign , Zoom AI,...

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