Director - Commercial Manufacturing Operations

Location: This position may be performed remotely but requires flexibility and a willingness to travel (approximately 40–60%) to CDMO manufacturing sites, including international travel as needed. The Opportunity Praxis partners with external manufacturers to produce life-changing medicines for patients with central nervous system disorders. This role exists to ensure those partners operate with the same urgency, quality, and accountability that we expect from ourselves. As Director, Commercial Manufacturing Operations, you will serve as the operational leader for commercial manufacturing of an assigned product. Acting as Praxis's "virtual plant manager," you will own day-to-day manufacturing performance across one or more CDMO partners, ensuring reliable supply, operational excellence, and continuous improvement throughout the commercial lifecycle. This is not a project management or technical transfer role. It is an operations leadership role focused on delivering consistent commercial execution through influence, partnership, and disciplined operational management. You'll build strong relationships across Manufacturing, Quality, Supply Chain, MSAT, Procurement, and our external partners to anticipate risks, solve problems quickly, and continuously raise performance standards. Success in this role means patients receive uninterrupted access to medicines because our manufactu...