Principal Scientist, Translational Oncology – Single Cell and Spatial Genomics, Solid Tumors

About the Role We are seeking a Principal Scientist to serve as a translational and strategic leader within our Oncology research organization. This role sits at the crossroads of reverse translation, biomarker science, and cutting-edge genomics technology — driving mechanistic insight from the clinic back into discovery to accelerate and de-risk our oncology pipeline. The ideal candidate brings deep expertise in cancer biology, a track record of cross-functional leadership in a pharma or biotech environment, and hands-on experience building and deploying single cell and spatial omics capabilities. What You'll Do Discovery & Translational Research Leadership  Drive discovery and translational projects in collaboration with AI and internal research teams with a primary focus on integrating scRNA-seq and spatial biology into Natera’s pipeline.  Collaborate with external translational teams on building single-cell and spatial biology workflows into their early phase clinical studies.  Leverage novel technologies to inform collaborative reverse and forward translation efforts as well as internal target discovery and validation projects.  Design and execute lab-based research programs that bridge clinical observations with mechanistic hypotheses, supporting asset progression and CDP expansion Technology & Capabilities  Lead and contribute to technology area team focused on sin...